Transplantation or transplantation of organs today is an increasingly accepted and successful method of treatment in the world but also in our country. The organs and tissues can also be transmitted. Transplantation also depends heavily on organ donors. Donors can be live or dead people. Everyone can be the organ donor unless he has objected to it in writing. Due to the shortest waiting time, Croatia is today, according to the number of transplantation and donor organs, the leading country in the world. In transplantation medicine, a nurse has a big role, except for surgeons and other health care staff without which transplantation would not be possible. Health care includes preoperative and postoperative treatment as well as essential education. The highest number of organs is obtained from the deaths of deaths. Without evidence of brain death transplantation it would not be possible to make this a necessary step for organ harvesting. In this paper I want to emphasize the need to donate and awaken humanity and nobility both in myself and in others because I consider transplants as a great opportunity to fight the many diseases that grow every day more and more.