Flu or influenza represents an acute infectious disease caused by influenza viruses A, B and C. It is a disease pertinent to respiratory system which is transmitted by airborne route from the infected patient. It appears every winter in form of minor or major outbreaks. The goal of this research was to explore attitudes, opinions and knowledge of the population regarding the flu and the flu vaccine. The research was conducted in the period from April 2nd to May 8th, 2019. A structured anonymous online questionnaire was used and the research was conducted on social networks. The questionnaire consisted of 16 questions where respondents were able to choose one of the answers. The study included 411 respondents in total. Sociodemographic features (such as gender, age, education, place of residence) were examined, followed by questions exploring attitudes, opinions and knowledge about the flu and the flu vaccine. Most respondents were female and the largest number of respondents were between 20 and 30 years of age. The results have revealed disparate views, opinions and information of the population regarding the influenza and influenza vaccine. According to the results, we can conclude that the majority of the population does not vaccinate, believes that the vaccine is not effective and will not vaccinate in the future; conversely, they believe that natural methods of ‘boosting immunity’ are a better option. Vaccination is considered one of the most salient medical interventions that prevents the development of disease; however, this study has shown that a large percentage of people does not vaccinate against the flu. Since the vaccine uptake is low basically every season, it is of utmost importance to educate the public about the flu and the flu vaccine, but also to individually carry out education endeavours that will include individuals with increased risk of flu complications in order to reduce mortality.