Stereotactic neurosurgery has a rich history. Several stereotaxic frameworks have been designed in order to increase the accuracy of stereotactic biopsy. Currently, the most commonly used frame is Leksell frame. The purpose of the frame is to accurately position the head within the coordinate system and to determine the coordinates of the target point intended for biopsy. In addition to biopsy of brain tumors, stereotaxy is also used for deep brain stimulation in patients with Parkinson's disease and dystonia. The latest stereotactic system is a robotic stereotactic and navigation system used for tumor biopsy and deep brain stimulation. High accuracy, with an error of less than 2 mm, is necessary for the success of the operation. Within thos master thesis the results of a cross-sectional study of the accuracy and effectiveness of biopsies performed using the robot "Ronna" in 30 patients are presented. In the continuation of the study, obtained results will be compared with the results of a classical biopsy performed using the Leksell framework. In the stereotactic biopsy with the Ronna robotic system, the error was 1.4 mm. Furthermore, the mentioned surgical procedure is shorter than the classic biopsy and enables a faster and easier change of the biopsy plan.