Gallbladder cancer, although considered rare is the most common form of malignancy in the biliary tract. It makes up 80% -90% of all malignant diseases of the biliary tract. Early diagnosis is necessary because the disease progresses quietly. Late diagnosis often proves fatal. Older age, female gender, congenital bile abnormalities, and genetic predisposition are important unchanged risk factors. Mortality rates are closely monitored by countries with the highest prevalence of gallstones. Nursing interventions are also related to patient and family education. The nurse / technician explains to the patient which therapeutic procedures will be performed during the treatment, including patients, conducting education on the course of the disease and changing some life habits. The nurse / technician provides psychosocial support to the patient and the family, which is extremely important in the adjustment process in knowing that the person is suffering from gallbladder cancer, and our goal is for the patient to establish normal life courses. General preoperative preparation is psychological and physical. The purpose of psychological preparation ensures the best readiness for surgery and reduction of anxiety. Physical preparation of patients for surgery includes examinations, adequate nutrition, patient education, and preparation of the digestive tract. The health care of operated patients is focused on the recognition of postoperative difficulties and complications, their reduction and / or removal.