Celiac disease is an autoimmune disease, an disorder that includes both innate and acquired immunity in genetically predisposed people. It appears with ingestion of gluten that causes immune reactions that causes changes in the stucture of small bowel mucosis that finally leads to the malabsorption of nutrients and the onset of the celiac disease symptoms. It most often occurs in the age of a small child or late infancy due to the inclusion of gluten-rich cereals in the diet, but there is also possibility that it can occur in every human age. Symptoms that come with celiac disease are abdominal pain and cramps, diarrheal stools of oily consistency or constipation, anemia, rickets, slower growth in children and adolescents, weight loss, fatigue or weakness. The method of choice when diagnosing celiac disease is a biopsy of the small intestinal mucosa. Complications of celiac disease resulting from non-adherence to a gluten-free diet are hyposplenism, refractory celiac disease, intestinal lymphoma, small bowel adenocarcinoma, ulcerative jejunoileitis, and celiac crisis. These are serious and life-threatening conditions. According to today's findings, celiac disease is considered a chronic incurable disease, but with the help of a strict gluten-free diet it is possible to keep the symptoms under control and completely eliminate the negative consequences of the disease. In order for the patient to easily and effectively master the necessary skills and knowledge related to living with celiac disease and implementing a gluten-free diet, it is important to educate the patient and his family by nurses and other members of the multidisciplinary team. Although celiac disease is defined as a chronic incurable disease, in very rare cases gluten tolerance has been reported in people who have been reintroduced gluten into their diet after many years of gluten-free diet and biopsy results suggesting complete regeneration of the small intestinal mucosa as shown in the case report of this paper.