Tuberculosis is known as the deadliest pathogen in the world, with the highest mortality rate, which as a disease has followed humanity throughout its entire history. The destructive nature of the disease and systemic influence have oftentimes changed the course of history. Tuberculosis is caused by Mycobacterium tuberculosis, which is tranfered via air droplets, and in most cases causes damage to the lungs and other respiratory organs. Risk factors which contribute to the infection and development of tuberculosis are: HIV infection, younger age, proximity from the infected case, socioeconomic factors such as poverty or employment. One key symptom of tuberculosis is chronic cough, which can and doesn't need to be productive. Diagnosis is places upon receiving the patients' personal data, conducting a general examination, microbiological sputum analysis, radiographic measurements and tuberculine skin test. Therapy has to include at least two antibiotics, since monotherapy of tuberculosis often leads to the bacillus developing a resistance to a singular antibiotic. A nurse has a unique, continued role to, through education and the proper installment of therapeutical and diagnostic procedures, raise general awareness concerning tuberculosis, but also other pandemic characteristic of other infectious diseases. In this thesis there will be a summary on the historical course of the disease, it's effect on humanity, risk factors, diagnostics, pathogenesis, symptoms, therapy, prevention and the role of a nurse in the care for a patient suffering from tuberculosis. The results of the cross-sectional study will be published in the scope of this thesis. The study was conducted with the prime goal of ascertaining the level of knowledge among the general population, to properly identify the areas which require the attention of public health officials and the general population.