There are more than 300 sign languages in the world and 70 million people who use sign language. It is used as a communication system to help the deaf and deaf-blind community for everyday interaction which includes hand gestures, visual movements, head and body signs, facial expression. Sign language is older than speech itself, numerous sign languages were born around the world independent of each other and no sign language can be identified as the first. In the Republic of Croatia, there are about thirteen thousand people who do not use the standard Croatian language, but Croatian sign language. According to the Law of the Republic of Croatia, Croatian sign language was defined as an official means of communication for deaf/deaf-blind people in 2015. Quality communication between the patient and the healthcare staff is the basis of good healthcare. For this reason, communication with hearing-impaired people is not of the same quality as with hearing people. The research carried out on the topic "Knowledge of the general population about Croatian sign language", the expected results were obtained, the knowledge of the general population is poorly, information about the basic concepts of deaf-blind culture is minimal, but the interest of the population in learning Croatian sign language is still visible. In the research "Communication of deaf-blind people with health care workers", conducted through an interview with users of the Association of the Deaf-Blind, the results obtained indicate the dissatisfaction of deaf-blind people with the entire health care system, dissatisfaction is mainly focused on difficult and incomplete communication.