Stress is defined as a state that results from the relationship between man and the environment and the assessment that the demands placed by it are beyond his capabilities. Stress occurs when these demands are so intense that the individual simply cannot bear them. Previous research has shown that workplace stress can have a number of negative personal and professional consequences, including reduced work quality, disinterest, dissatisfaction, depression, anger, frustration, headaches, low self-esteem, extended sick leave and a lower likelihood of returning to work. In the last decade, work-related stress has been recognized as an important global public health problem. Although stress occurs in various professions, it is most pronounced in the educational sector. The main causes of this problem are the excessive volume of administrative work, teaching in several different institutions and subjects in order to achieve a full hourly rate, which additionally burdens the working capacity of teachers and negatively affects interpersonal relations within the collective. This paper investigates how workload and burnout affect professors and teachers, especially in the context of their motivation, job satisfaction, and interpersonal relationships. The focus is on understanding how stress affects the attitude of professors towards colleagues, students and others with whom they work, with a note that competent institutions should really work on improving working conditions in the education sector, in order to tackle the aforementioned problems.