By the significance of its actions, tourism is one of the integral parts for the economy of most of the countries of the world. Due to the rapid changes that happen on the global market, one could say that tourism is also subject to the everyday changes to which touristic destinations should adapt quickly in order to remain competitive and sustainable. Destionations that have not recognized the importance of exploring and managing at the right moment today most certainly are late for their competition. Similar story happened in Krapinske Toplice, one of the most well-known spa destinations in 19th and 20th century in this region. Krapinske Toplice are not recognized as the leading spa for both summer and winter time and as a place for multiday retreat anymore. However, they are known for their medical institutions and the benefits of the thermal water. One of the trends in tourism is market segmentation according to the motivation for the arrival to the destination and development of the specific types of tourism whose positive effects have been recognized by many destinations all around the world. One of the most dynamic specific types of tourism is most certainly medical tourism whose trend shows that the number od the people that enjoy medical-tourist offer is growing faster than the average growth of tourism. Creating medical-tourist offer seems to be a challenge for the tourist workers, and asks for the cooperation of both public and private sector. The aim of this work is to explore the trends of medical tourism, what it constitutes of and what are the specific features of the medical-tourist product. After that, the destination of Krapinske Toplice and its features will be analyzed with the aim of creating the guidelines for the development of the marketing strategy with the aim of development of Krapinske Toplice as a destination of health tourism.