Celiac disease is a chronic autoimmune disease that results from the intake of gluten and its related proteins found in wheat, rye, and barley, and can also be found in oats. It occurs more often in people who have a genetic predisposition. It is classified as one of the most common chronic diseases of children and adults, and thought to affect about 1% of the total population of Europe. For many the disease remains undiagnosed and unrecognized for a long time, which largely depends on the awareness of patients, physician awareness, the recognition of the symptoms of the disease in time and the availability of extremely accurate diagnostic methods. The gold standard for proving the diagnosis of celiac disease with positive serology is a biopsy of the small intestinal mucosa. Mass screening for the disease is not being conducted for the time being since there are still no uniform criteria. The only effective and proper treatment for celiac disease is a strict gluten-free diet. Celiac disease is a disease that is lifelong, and if left untreated it leads to numerous and very serious health complications, and at the same time affects the quality of life of patients. The aim of the research within this hesis was to examine the quality of life of patients with celiac disease in northwestern Croatia. The research approach entailed a quantitative approach and included 49 participants from the area of northwestern Croatia. A smaller sample was used due to the relatively small number of such diseases, and the survey was conducted in August 2021. To obtain data in the research, a survey questionnaire was used, which was independently developed for the purposes of conducting this research. Participation in the questionnaire was anonymous and voluntary. The obtained results indicate the main problems of celiac patients, which are mainly related to insufficiently available gluten-free products in stores, the lack of gluten-free menus in kindergartens and schools, and the availability of gluten-free meals in restaurants and bakeries. According to this research, it is important to point out that health professionals very rarely consider the emotional effects of living with celiac disease, as well as providing psychological support with professional help. An important role is played by the nurse, who with her knowledge and skills influences the information and well-being of people with celiac disease, as well as the inclusion of empathy and psychological support. We concluded that the respondents, despite the problems they expressed, have a certain dose of optimism and relatively modest satisfaction with life.