In the human body, the liver is one of the most important organs. Liver cirrhosis is a diffuse disease characterized by fibrosis and conversion of normal liver structure into structurally abnormal nodules that have lost their normal lobular organization. The normal structure of the liver is completely destroyed by fibrous tissue, which leads to liver shrinkage. Cirrhosis of the liver occurs as a result of various forms of disease that cause damage to the liver and liver cells. Cirrhosis of the liver is the last stage of chronic liver disease, which results in a series of pathophysiological disorders and clinical manifestations, which in individual patients can appear in different combinations or independently. Complications that develop in advanced liver cirrhosis are portal encephalopathy, portal hypertension, variceal bleeding, splenomegaly, ascites, liver cancer and hepatic coma. The ranking of the HZJZ from 2020 places cirrhosis of the liver in the 10th place as a cause of death in men in the Republic of Croatia. The aim of this thesis is to describe in detail the general characteristics of patients hospitalized in the OB Virovitica in the internal department due to cirrhosis of the liver in the period from 01.01.2019. until 31.12.2021, including age and sex, and the clinical characteristics of these patients, with regard to the discharge diagnosis, the number of rehospitalizations, urinary tract infections and the distribution of comorbidities with regard to gender, and the association of mortality with portal hypertension, toxic encephalopathy and alcoholic hepatitis. The data of the patients included in this research were collected for each individual patient from the hospital medical records at the Virovitica General Hospital in the internal department and were then collected in a table prepared and intended for this purpose in the Microsoft Excel 2019 program. Statistical analysis and data processing were performed on the collected data and connections between predefined variables are shown. The results of the research are presented by showing the frequency of individual values associated with the collected variables and by calculating the odds ratio (OR) with 95% confidence intervals (CI) and p-values for the tested hypotheses. In the conclusion of this thesis, I would like to look at the possibility of improving the quality of life of patients suffering from cirrhosis of the liver, all with the aim of achieving their personal satisfaction, as well as the quality of the immediate and wider social community. In the very process of healing, the support of the patient's family is the most important for the patient during hospitalization in a health facility and after the patient's discharge from the hospital. It is very important to educate the patient and his family about the disease itself and its complications, as well as involving multidisciplinary teams in the process of treating the patient and involving the patient and family in the club of treated alcoholics (KLA).