According to a definition by the International Association for the Study of Pain, "pain is an unpleasant sensory and emotional experience associated with tissue damage or described in terms of that damage." Nowadays, pharmacological methods are most often used to treat pain, but non-pharmacological methods of treating pain also have a very good effect on pain. Pain is still not sufficiently researched, although there is progress in the field of health. For the nurse it is important that she has an understanding for mentally ill people when they state or show that they are in pain. It is also very important for her to trust them. In order to provide effective nursing care, the nurse plans nursing interventions based on the assessment of pain in psychiatric patients and her knowledge of pain. In cooperation with the patient, she selects and applies pain relief procedures. In some cases, pain can be the cause of deterioration of the symptoms of psychiatric illness. This paper will define the concept of pain by showing its association with certain psychiatric diseases. It will also present the most used non-pharmacological methods of pain treatment applicable in working with patients suffering from psychiatric diseases. Such an approach can improve the quality of life of the psychiatric patient and reduce stress, feelings of helplessness and tension as well as the negative consequences of pain.