The COVID-19 pandemic has significantly impacted the global economy, particularly affecting small businesses, which have faced numerous challenges and issues. This thesis analyzes the impact of the COVID-19 pandemic on the operations of small businesses in Varaždin County, with a special focus on changes in business practices, financial stability, and adaptations during the crisis. The paper explores the key challenges faced by small businesses in Varaždin County during the pandemic, including reduced revenues, liquidity problems, disruptions in supply chains, and changes in consumer behavior. Various strategies implemented by businesses to adapt to the new circumstances, such as business digitalization, the introduction of new products and services, and the optimization of operational costs, are also analyzed. Special emphasis is placed on the role of government support measures and local initiatives aimed at preserving jobs and maintaining business activity. Through the analysis of available data and research conducted among entrepreneurs, the paper provides insight into the effectiveness of these measures and their role in mitigating the negative effects of the pandemic. The research findings indicate that small businesses in Varaždin County demonstrated remarkable resilience and adaptability in facing the crisis but also encountered long-term challenges that require further adjustments and innovations. The paper also suggests guidelines for strengthening the resilience of small businesses in future crisis situations, including further digitalization, diversification of business activities, and strengthening cooperation with the local community. This thesis contributes to the understanding of the impact of the COVID-19 pandemic on small businesses and provides relevant recommendations for policymakers and entrepreneurs aimed at strengthening economic resilience and sustainable development in the region.