We live in a century which is on global scale marked by great public health issues in the form of cardiovascular diseases. On the annual level, the treatment of these diseases is largely funded. Number of factors lead to the development of cardiovascular diseases. Variable factors can be affected, and by altering them, the possibility of the occurrence of the disease can be reduced. Invariable factors are made by that which is genetically determined. There are also various environmental factors, such as atmospheric influence, which can have negative effect on human body. The goal of this research is to determine connection between the atmospheric pressure and the number of patients who were admitted to Institute of Emergency of Zagreb County with certain symptoms and diagnosis of cardiovascular system. According to the data collected by National Hydrometeorlogical Department and the data concerning the number of patients from the system of Institute of Emergency for period 01.01.2015 to 31.12.2015. I got the number of 53 867 admitted patients, of which 7 934 had the diagnosis from the target group, 3 513 men and 4 421 women. In relation to the obtained data on medium air pressure from the Grič (Zagreb) measuring station, which values are divided into four groups of air pressure, the results have shown that there is a difference in arrivals of the air pressure group from 990,1 to 1000 hPa in favor of female gender. 4146 patients have reported due to the aliments connected to the cardiovascular system. Of total number of patients for that group of air pressure, women reported in 2350 cases (56,68%) and men in 1796 cases (43,32%). Certain numbers of diagnosis only appear depending on the season, the number of patients with hypertension and the insufficiency of the heart is statistically significant during the winter. Correlation analysis of the air pressure and diagnosis did not show the connection between the incidences. It would be interesting to conduct further research in the future, on the topic of influence of atmosphere pressure and other parameters such as temperature and humidity, on the incidence of symptoms of cardiovascular diseases.