Acute myocardial infarction occurs when the blood flow to the heart muscle is suddenly interrupted, causing tissue damage and thus endangering the life of the affected person. Acute myocardial infarction is actually necrosis of the myocardium which is a consequence of acute coronary artery obstruction. Symptoms can vary, but most commonly include chest discomfort with or without dyspnea, chest pain that may radiate to the left arm or upper body. With a detailed history and clinical picture of the patient, the diagnosis is confirmed by electrocardiogram (ECG) and the presence or absence of serological markers. The treatment is individual, and it requires urgent medical care for the patient in order to start it within the given time frames. The continuation of treatment is reduced to rehabilitation of the patient and secondary prevention, which aim to change the lifestyle of the patient with the purpose of preserving the quality of life and reducing the risk of developing a new cardiovascular disease. Nurses/technicians have an exceptional role in acute patient care and as educators on lifestyle changes. The paper analyzes the causes, procedures and methods of treatment and the role of nurses/technicians in patients suffering from acute myocardial infarction. Two case presentations show the clinical picture of acute myocardial infarction, the course of the disease and treatment.