This thesis explores the knowledge and experinces of nurses/technicians regarding Clostridioides difficile infection. Clostridioides difficile infection poses a challenge to the healthcare system, requiring careful management to prevent the spread of infection and provide appropriate care to patients. Nurses/technicians play a crucial role in infection prevention and control in healthcare facilities, making their knowledge, experinces and practices of paramount importance. Questionnaires gathered data on the knowledge of nurses/technicians about the infection, their attitudes towards infection prevention and management, and their experiences working with patients infected with Clostridioides difficile. The research findings provide valuable guidance for enhancing the education of nurses/technicians about Clostridioides difficile infection and developing improved protocols for infection prevention and management. This study also aims to raise awareness about the importance of infection prevention and control among healthcare workers. This thesis contributes to the existing body of knowledge on Clostridioides difficile infection and will stimulate further research and initiatives focused on prevention and management of this infection.