Complementary and alternative health and medical practice KAM is a group of different medical and health systems, practices and products that are not currently considered part of conventional medicine. Alternative medicine refers to therapeutic approaches that are used instead of traditional medicine and are used to treat or alleviate disease. The underlying philosophy of complementary and alternative medicine includes holistic care that focuses on treating the person as a whole person. The endless variety of practices are scientifically unproven and poorly accepted by medical authorities, so in order to organize a strategy for researching KAM approaches, the US National Institutes of Health grouped KAM methods into 5 main groups: biologically based practices, manipulative and body approaches, medicine mind and body, alternative medical systems and energy medicine. Motivated by personal experience and seeing the above-mentioned situations, my goal was to investigate how well informed patients are about complementary and alternative methods, what is the frequency of use, which methods are chosen as the most common among patients and how they learn about them. The research was conducted using a Google form, in the period from October 17, 2022. until May 17, 2023. The research was voluntary and anonymous, and oncology patients in the Republic of Croatia participated, mostly in the northern part due to the groups and areas of social networks in which the form was shared. 410 respondents were included. The questionnaire for the implementation of the research consisted of 3 parts: a general part that collected sociodemographic data (gender, age, level of education, employment status and the environment in which the respondent lives), the second part with questions focused on the disease and the type of treatment the respondents received subject to the third part, questions that were aimed at the information of the respondents and the widespread use of complementary and alternative methods. The results show a large number of respondents who are informed about complementary methods, but on the other hand, a part of patients who have not even heard of such treatment methods. Most often, natural methods are used in the form of phytotherapy, while spiritual methods are used somewhat less. A worrying fact is that patients usually do not inform anyone about the use of complementary and alternative treatment methods; a significant percentage of 53.20% is visible. Such information speaks in favor of the fact that there is still a barrier in the relationship between the healthcare team and the patient, which is the reason for the patient's fear of discussion and possible interests in other methods of treatment that are not part of conventional medicine.