Cleft lip and/or palate is a tissue defect caused by the separation of previously normally structured tissues. It is a congenital malformation of the face that occurs because of incomplete development of the lip and/or palate in the early weeks of pregnancy. Clefts make it difficult for the newborn to feed and breathe, and later affect the development of teeth, hearing and speech. Cleft treatment is exclusively surgical, long-term and involves several a multidisciplinary team. In the territory of the Republic of Croatia, cleft lip and/or palate operations are performed only at the Dubrava Clinical Hospital. Successful repair of cleft lip and/or palate requires good coordination of all members of the multidisciplinary team. In every phase of treatment, a nurse is an indispensable member of the team. This thesis describes the importance of the nurse's role in the overall functioning of the multidisciplinary team and coordination among team members, and statistically processed data on the frequency of clefts, maternal age, genetic predisposition, and geographic location in the period from 2018 to 2022.