Patients come for initial and maintenance rehabilitation based on the approval of the Croatian Health Insurance Institute (HZZO), after trauma, various operations, chronic degenerative changes, congenital conditions and inflammatory changes in the joints. Such conditions are often accompanied by a certain level of pain. Research from our country and around the world has shown that only a quarter to half of patients are prescribed adequate analgesic therapy. The research within this thesis was conducted with the aim of examining the presence of pain in patients and its level, the prescribed analgesic and other therapy, the practice of self-prescribing analgesics, the method of obtaining self-prescribed drugs, and the patient's knowledge of possible complications related to analgesic therapy. The research included 100 patients, an equal number of patients undergoing initial and maintenance rehabilitation. Their answers showed that 81% of respondents felt pain during admission. Patients in the initial rehabilitation most often rated the pain on the VAS scale 1-10 as 5, and patients in the maintenance treatment as 6. The results show that 72% of the respondents have prescribed analgesic therapy, and 63% of them take medication according to the doctor's recommendation. This research proved that 47% of patients arbitrarily adjust the prescribed dose of analgesics, whether they reduce or increase it, while 59% of them prescribe analgesics themselves. The most common analgesic used in self-prescription is Ibuprofen. Respondents most often buy non-prescribed medicines at a pharmacy and get them from family members. 76% of them, consume various other drugs in addition to analgesics, which can have an impact on their pharmacodynamics and pharmacokinetics, and lead to side effects and stress on various organ systems. By determining the respondents' knowledge of complications related to the use of self-prescribed analgesics, it was proven that 47% of them do not know how to list the complications, from which it can be concluded that a relatively low level of knowledge was demonstrated, which leaves room for additional patient education.