Carpal Tunnel Syndrome is a common neuropathic disorder caused by pressure on the median nerve within the carpal tunnel. Pregnant women are particularly prone to this condition due to physiological changes that occur during pregnancy, such as fluid retention and swelling. The clinical presentation of Carpal Tunnel Syndrome in pregnant women includes symptoms such as tingling, pain, weakness, and loss of hand function. Differential diagnosis methods are employed to distinguish Carpal Tunnel Syndrome from other similar conditions. Diagnostic methods include electromyography and nerve conduction velocity testing. Proper physical therapy assessment, along with the use of clinical functional tests and questionnaires, provides insight into the current progression of the syndrome, leading to the development of an individualized therapy plan aimed at pain reduction and, ultimately, a better quality of daily life. Special attention is given to conservative treatment methods recommended during pregnancy, such as wearing wrist splints, applying cold packs, and performing stretching and strengthening exercises for the hands. Proper education of pregnant women enables them to continue exercising and following prescribed methods even after treatment has ended. The conclusion highlights the importance of timely diagnosis and adequate treatment to alleviate symptoms and prevent long-term complications. This allows pregnant women to achieve a better quality of daily life and improved hand functionality, which is crucial for their overall health and well-being.