Objective: This final paper was made for the purpose of researching the knowledge of the general population about infectious mononucleosis in order to emphasize the importance of educating the population. Methods: The above survey was conducted using a survey questionnaire that included 125 respondents of different sexes age groups and socioeconomic status. The survey was distributed using the Google Forms platform on various social networks and consisted of 16 questions. For statistical analysis the data are displayed using graphs. Results: by investigating the knowledge of the general population about infectious mononucleosis we received a better and clearer insight in the knowledge of the above mentioned disease. The results showed a greater interest in women for this topic. It is also clear from the obtained results that more young than the old population took part in the survey which can be overwritten that the survey was published in digital form on social networks that have no such access to the elderly population. Most respondents showed satisfactory knowledge of the general symptoms and ways to treat infectious mononucleosis while the rest of the respondents are not so familiar with the disease. We can also say that it is the younger population that most often suffers from this disease but most of them do not report the symptoms to their primary care physician. Conclusion: from the above research results it is concluded that there are still many places to educate the population about the infectious mononucleosis disease itself the symptoms that appear and the methods of treatment. Reporting symptoms to your primary care physician is extremely important in order to react in a timely manner and reduce the number of patients accordingly. Medicine is advancing every day so the topic of developing a vaccine against the EBV virus should not be ignored. The role of a nurse is important in educating and supporting the patient and their family. The nurse provides information and assistance in overcoming symptoms of the illness reduced tolerance to exertion insomnia and the importance of diet therapy.