The spectrum consisting of inflammatory bowel diseases are ulcerative colitis, Crohn's disease and unclassified inflammatory bowel disease. Symptoms of these diseases strongly affect physical and psychosocial functioning of patients, often involving intestinal complaints such as nausea, vomiting, diarrhea, fresh blood in the stool, pain in the abdomen, unwanted weight loss, and many other symptoms. Ulcerative colitis is characterized by continuous chronic inflammation of the lining of the rectum and colon. Crohn's disease is a chronic inflammatory bowel disease of unknown etiology that may affect any part of the gastrointestinal tract, from the mouth to the anus. Unclassified inflammatory bowel disease is a term that describes patients in which, following a detailed evaluation, can not be distinguish whether it is ulcerative colitis, Crohn's disease or some other form of colitis. The clinical approach to patients with inflammatory bowel disease involves several steps: diagnosis, defining phenotype, assessment of the extent and activity of disease, detection of extraintestinal manifestations and evaluation of the effectiveness of previously used therapies. Due to frequent hospitalization major role in the health team has a nurse, who with particular knowledge and skills through health care and education helps the patient in dealing with its problems. Nursing of patients with inflammatory bowel disease depends how much is intestine affected and primarily on the general condition of the patient.