Colon cancer today is one of the largest and the leading health problems in the world in both sexes, particularly in highly developed countries. In our country occupies half the frequency of the second place among malignancies, in males the most behind lung cancer, and in the woman behind the increasing breast cancer. The incidence of the disease is growing and is doubled every ten years after you reach 40. Preventive tests and previews can be detected at an early stage, but the unwillingness of the "healthy" person in such form of health protection results in setting the diagnosis only after the onset of symptoms by two-thirds of the patients. The choice of treatment depends on the type, localization and advance of malignant processes, and is multidisciplinary, which means that in the great majority of patients apply multiple forms of treatment (two or three), or most commonly after the procedure of surgical treatment, the patient must do chemotherapy, or a combination of chemotherapy and radiation. Intestinal stoma is an opening made artificially after surgery (resection) of part of the colon that is performed on the front abdominal wall, where he actually has the function of rectum in patients. If it's not performed in adequate surgical technique, and if it's not properly nurtured, there are numerous complications in patients. For this reason it is essential to devote the proper quality health care to make it better and shorter recovery of such patients. Apart from the role of the physician, of great importance are the nurses and enterostomal therapists that with their knowledge educate patients to adapted more easily to the new situation and had a better quality of life in the future. Assessment of the quality of life today is an integral part of the evaluation of rehabilitation and therapeutic procedures. The quality of life in the narrowest sense, defined as overall well-being that are affected by objective indicators and subjective perception of the person, the evaluation of emotional, physical, social and material well-being. The patient should learn and take the skills and procedures that would take him throughout life, and be adequately and well educated about them by the medical staff. The greatest importance on the quality of life after the operation contributes to the family, who is with the patient's great most of the time, supports him and helps him in for future recovery and aspects of life of the patients.