In medical practice I also look forward to people, especially to patients an important trait built on self-esteem. It leads us to success satisfied in all segments. It’s not easy, it’s usually treated as a very stable feature of an individual, and that can hardly be changed. The questionnaire “The impact of hospitalization on patients' self-esteem” was proven in the period from 01 April to 30 July 2019 through anonymous questionnaires. It consisted of two sections, 8 general sociodemographic questions and 10 questions within the Rosenberg Self- Esteem Scale (RSS). The aim of the study was to examine how patients perceive themselves, how much self-esteem they have while pursuing nursing care in clinical practice and whether there are differences in patient's satisfaction with provoking nursing care in clinical practice due to the number of hospitalization days. A total of 50 subjects participated in the proven study of which the chronologically youngest was 30 years old and the oldest was 83 years old. Out of the total number of respondents, 46% are male and 54% are female. Considering the place of residence, it was found that 72% of the respondents live in rural areas and 28% of the respondents live in city. Most of the respondents have a university degree, 70%. Higher education has 12% of respondents, and 18% of completed compulsory primary education. The impact of hospitalization greatly affects the self-esteem of the patient, and that the nurse who spent the most time with the patient herself has the highest self-esteem of maintaining high power.