Beta-haemolytic group A streptococcus or Streptococcus pyogenes is a Gram-positive bacterial species that can cause many diseases such as erysipelas, pharyngitis, tonsillitis, scarlet fever, etc. Erysipelas represents an acute or chronic recurrent disease characterized by fever, malaise, and inflammatory or purulent lesions with clearly demarcated areas of the skin. In other words, it can be defined as an infectious-allergic clinical entity caused by beta-haemolytic group A streptococcus, and is characterized by serous and serous-haemorrhagic focal inflammation of the skin and mucous membranes, fever, as well as a strong systemic reaction of the organism. In addition to primary diseases, it causes complications in the form of purulent manifestations such as cellulitis and peritonsillar abscess, and can cause systemic immune reactions in the form of rheumatic fever, arthritis and poststreptococcal glomerulonephritis. As a part of this thesis, the aim was to present the etiological and epidemiological factors of infection with beta-haemolytic streptococcus group A, the disease it causes with emphasis on erysipelas, and to show the extent of knowledge of nurses and technicians about this bacterial agent and its virulence, but also attitudes related to it. A study was conducted in which 213 nurses and technicians working from different departments participated, of which 68 respondents had secondary education, while there were 107 bachelors of nursing. Respondents answered questions related to knowledge of the aetiology of the disease, but also to questions related to infection transmission, treatment and prognosis. The results of this research demonstrate that nurses and technicians are not completely familiar with beta-haemolytic group A streptococcus, etiological and epidemiological factors of infection, bacterial virulence, treatment and complications that can occur with this infection.