Breast cancer is known as the leading and most common oncological disease in women. Also, it has been proven that the lowest incidence rate of cancer is in women under the age of 25 and the highest in postmenopausal women. Nowadays, breast cancer can be detected at a very early stage and therefore the possibility of cure is very high. Early detection of breast cancer is performed by breast self-examinations and preventive mammography. The vast majority of patients feel an asymptomatic lump or are detected during a screening mammogram. The diagnosis is then confirmed by biopsy. Treatment is surgical, radiation and systemic hormonal and/or chemotherapeutic and/or immunotherapeutic treatment, and its combination gives the best results. The aim of this study was to find out what is the perception in terms of disease prognosis in patients with metastatic breast cancer in nurses. 152 respondents participated. A 25-question questionnaire constructed for the purposes of this research was used. The questionnaire collects sociodemographic data and examines the cognitive and emotional components of nurses' attitudes toward patients with metastatic breast cancer. Descriptive methods and examination of differences in statistical data analysis were used. The data were processed in the statistical program SPSS - Statistic for Windows. Participants did not differ statistically significantly in their attitudes toward working with oncology patients according to whether they lived in urban or rural settlements. The nurses/technicians in this study did not differ significantly in their attitudes towards working with cancer patients according to whether they work in primary, secondary, or tertiary care. The need for continuous and additional education in the direction of approach to the patient, the way of talking to him, informing him about the next steps, his rights is emphasized. When providing psychological help, they pointed out that a larger number of psychologists and/or psychiatrists in oncology wards is needed, that a psychologist/psychiatrist should be present when diagnosing a patient, that medical staff should be provided with psychological help and support in the form of support groups a workshop on various psychological topics crucial in working with oncology patients and individual conversations with psychologists.