Depression is a disease characterized by changes in mood, such as prolonged sadness and the inability to enjoy things and activities that were previously a source of happiness and satisfaction for the individual. In addition to the basic symptoms, symptoms such as changes in appetite, insomnia, restlessness, inability to concentrate, memory problems, feelings of guilt and worthlessness, lack of energy also appear. The disease affects the performance of everyday, most important activities because it impairs the patient's ability to function normally. Also, depression leads to the destruction of family, friendship and business relationships. If depression lasts for a long time without adequate treatment, suicidal thoughts and suicide attempts occur in some individuals. Depression is a major public health problem because recently the number of patients is increasing and the death rate is increasing due to the appearance of other physical diseases and suicide. It is important to seek the help of a specialist when the first symptoms suggestive of depression appear, in order to establish a diagnosis as early as possible and implement a safe and effective treatment that will be adapted to each individual. The research was conducted with the aim of checking the knowledge of nursing students about depression and finding out the risk of developing depression in their population. 102 nursing students from the first to the third year participated in the survey. 73 (71.6%) research participants were female, and the other 29 (28.4%) were male. Most of the participants were from the third year of nursing, 44% of them. The vast majority of participants are not employed in the profession. By analyzing the obtained data, we can conclude that nursing students do not have negative attitudes or stereotypes about depression patients. 30% of the research participants felt the presence of symptoms of depression at the time of filling out the survey. The obtained data show a high rate of depression symptoms in young people, in this case nursing students. In the case of most of the participants, the symptoms of depression occurred during their studies due to daily exposure to high levels of stress. Due to inadequate ways of coping with stress, some research participants often feel worthless and express dissatisfaction with their lives and think that other people are more satisfied than them. Based on numerous researches, it is concluded that depression is a disease that is increasingly present and that all people are equally prone to the development of the disease, regardless of gender, age and level of education. Depression has become a major public health problem and it is necessary to carry out education from an early age in order to prevent the onset of the disease in later life.