The COVID-19 pandemic has created a public health crisis infecting millions of people and causing a significant number of deaths. SARS-CoV-2 is transmitted from person to person by several routes, mainly through respiratory droplets, making it difficult to contain the spread. Although the disease has not yet been fully researched, the most well-known symptom so far that people have expressed is the loss of taste and smell. Treatment is symptomatic and therefore individual. In the fight against infectious diseases, enormous progress has been made in the field of vaccines. Vaccines against the SARS-CoV-2 virus are still under the magnifying glass and people are still afraid of them. There are four registered vaccines in the Republic of Croatia so far, namely: Spikevax-Moderna, Comirnaty BioNTech Pfizer, Janssen-Johnson & Johnson and Vaxevria-AstraZeneca. It is necessary to develop public awareness of the usefulness and benefits of vaccination through research and education in order to reduce fear in the community. Within this research, which was conducted in the period from 31st of April 2022 until 25th of July 2022, all topics of interest to citizens in terms of the disease Covid-19 and the SARS-CoV-2 virus itself were covered. The aim of the research was to examine the knowledge of the inhabitants of Sisak-Moslavina County about the origin of the virus itself and the development of the disease. It is of great importance to see what preventive measures the inhabitants use in the fight against disease. The percentage of vaccinated research participants is important so it can be compared with the rest of the registered vaccinated individuals within the Republic of Croatia. The survey includes a total of 30 questions most of which are of the multiple choice question type, two of which are open questions and a few yes/no questions. Only residents of the Sisak-Moslavina County who were over 18 years of age participated in the research. The research results are not unusual and all three hypotheses were confirmed. Regarding the questions asked about the research participants knowledge about the virus 58.7% know the place of origin of the virus and even 75% of research participants correctly answered when the virus first appeared. It turned out that the 76% of research participants in the Sisak-Moslavina County have been vaccinated and 68.3% would recommend their relatives to get vaccinated. Such figures indicate good information within the county and strengthened people's awareness. As for prevention measures 54.8% of people wore protective masks during the pandemic, 42.3% were careful about social distancing and 65.4% of research participants took more care about hand hygiene. Through research, we conclude that a large number of people are well informed and familiar with the diseases of COVID-19, the way it spreads and how to prevent it.