Introduction: Hemodialysis treatment involves the filtration of waste materials and water from the bloodstream. In patients diagnosed with chronic kidney disease, hemodialysis replaces reduced or lost kidney function. The course of hemodialysis includes extracorporeal blood circulation, where the blood passes through the blood lines and the dialyzer, where waste substances and water are filtered out of the body. The start of hemodialysis treatment turns the patient's life around. Various restrictions are imposed that affect the patient's quality of life. Due to the influence of numerous factors, the quality of life of hemodialysis patients deteriorates. It is necessary to improve the quality of life of a hemodialysis patient through systematic observation and assessment. Hemodialysis is a treatment method that changes and saves life, but also changes the patient's quality of life. The course of treatment occupies most of the attention, while the patient's priorities and quality of life are neglected. Quality of life means a state of complete physical, mental and social well-being. Research goals: To investigate the occurrence of problems that affect daily functioning in life before and after hemodialysis treatment. Determine the opinion and attitude about one's own quality of life, the present signs that reduce the patient's quality of life, and the recognition and suppression of bad habits that affect the quality of life. Methods: The research was conducted at Varaždin General Hospital in the Hemodialysis Center from August 30 to September 6, 2024. The implementation of the research required the approval of the Ethics Committee of Varaždin General Hospital. An anonymous survey was conducted, which contained 19 questions, of which the first four questions were related to sociodemographic characteristics, and the other 15 were related to examining attitudes and opinions about the quality of life. 76 patients out of a total of 87 on a chronic hemodialysis program participated in the study. The obtained data were processed using Microsoft Excel and presented using graphs and tables. Results: Data analysis revealed that in the population of elderly people, satisfaction with their own quality of life prevails, regardless of the presence of physical and cognitive limitations and/or impairments. Comparatively, the younger population is more dissatisfied with their own quality of life. Conclusion: The quality of life of hemodialysis patients decreases due to the influence of numerous factors. By assessing the emotional and physical state, the nurse/technician in collaboration with the nephrologist plans and implements interventions to improve the quality of life of patients on a chronic hemodialysis program.