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undergraduate thesis
Zdravstvena njega bolesnika oboljelog od Hodgkinova limfoma
2023. urn:nbn:hr:122:825833
Kralj, Danijela
University North
University centre Varaždin
Department of Nursing

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Kralj, D. (2023). Zdravstvena njega bolesnika oboljelog od Hodgkinova limfoma (Undergraduate thesis). Koprivnica: University North. Retrieved from https://urn.nsk.hr/urn:nbn:hr:122:825833

Kralj, Danijela. "Zdravstvena njega bolesnika oboljelog od Hodgkinova limfoma." Undergraduate thesis, University North, 2023. https://urn.nsk.hr/urn:nbn:hr:122:825833

Kralj, Danijela. "Zdravstvena njega bolesnika oboljelog od Hodgkinova limfoma." Undergraduate thesis, University North, 2023. https://urn.nsk.hr/urn:nbn:hr:122:825833

Kralj, D. (2023). 'Zdravstvena njega bolesnika oboljelog od Hodgkinova limfoma', Undergraduate thesis, University North, accessed 09 April 2025, https://urn.nsk.hr/urn:nbn:hr:122:825833

Kralj D. Zdravstvena njega bolesnika oboljelog od Hodgkinova limfoma [Undergraduate thesis]. Koprivnica: University North; 2023 [cited 2025 April 09] Available at: https://urn.nsk.hr/urn:nbn:hr:122:825833

D. Kralj, "Zdravstvena njega bolesnika oboljelog od Hodgkinova limfoma", Undergraduate thesis, University North, Koprivnica, 2023. Available at: https://urn.nsk.hr/urn:nbn:hr:122:825833

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Metadata
TitleZdravstvena njega bolesnika oboljelog od Hodgkinova limfoma
Title (english)Health care of a patient with Hodgkin's lymphoma
AuthorDanijela Kralj
MentorMelita Sajko (mentor)
Committee memberDuško Kardum (predsjednik povjerenstva)
Committee memberMelita Sajko (član povjerenstva)
Committee memberValentina Novak (član povjerenstva)
GranterUniversity North
(University centre Varaždin)
(Department of Nursing)
Koprivnica
Defense date and country2023-07-10, Croatia
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Nursing
Abstract
Hodgkinov limfom jedan je od sve učestalijih hematoloških zloćudnih bolesti s incidencijom od oko 3 slučaja na 100 000 osoba godišnje te se upravo navedenom dijagnozom bavi ovaj završni rad. Pregled literature pokazuje da HL ima osebujnu dobnu distribuciju s prevalencijom ne samo u starijoj životnoj dobi, već i kod mlađih odraslih osoba, što ga čini jednim od najčešćih karcinoma u ovoj dobnoj skupini. HL ima stopu izlječenja od 80 do 90% s kombiniranom kemoterapijom i radioterapijom što ga... More ubraja među limfome s dobrom stopom izlječenja. Novi pristupi liječenju, posebno s inhibitorima imunoloških kontrolnih točaka te transplantacijom matičnih stanica pokazuju obećavajuće rezultate u poboljšanju izlječenja i smanjenju nuspojava i dugotrajne toksičnosti povezane s konvencionalnom terapijom. HL dijeli se u četiri glavna oblika: klasični HL miješane celularnosti (MCCHL), Hodgkinov limfom bogat limfocitima (LRCHL), Klasični Hodgkinov limfom s osiromašenim limfocitima (LDCHL) te HL s prevladavanjem nodularnih limfocita (NLPHL). Tumorske stanice koje prevladavaju u navedenoj bolesti nazivaju se Hodgkinove i Reed-Sternbergove (HRS) stanice. Ovi oblici HL razlikuju se u morfologiji i imunofenotipu stanica limfoma, sastavu mikrookruženja limfoma i njihovom kliničkom ponašanju. Dok je liječenje HL-a velika priča o uspjehu i iako je HL prvi limfoidni zloćudni tumor koji je prepoznat s prvim opisom prije više od 150 godina, njegova biologija i patogeneza dugo su bile zagonetne. Glavni razlog tome je rijetkost tumorskih stanica u zahvaćenim limfnim čvorovima, što je uvelike otežavalo njihovu molekularnu analizu. U sklopu ovog rada analizirala se zdravstvena njega bolesnika oboljelih od Hodgkinova limfoma koja predstavlja velik izazov u sestrinskoj skrbi. Less
Abstract (english)
Hodgkin's lymphoma is one of the increasingly frequent hematological malignancies with an incidence of about 3 cases per 100,000 people per year, and this final thesis deals with the diagnosis mentioned above. A review of the literature shows that HL has a peculiar age distribution with a prevalence not only in older age but also in younger adults, making it one of the most common cancers in this age group. HL has a cure rate of 80 to 90% with combined chemotherapy and radiotherapy,... More making it one of the lymphomas with a good cure rate. New treatment approaches, particularly with immune checkpoint inhibitors and stem cell transplantation, show promising results in improving healing and reducing side effects and longterm toxicity associated with conventional therapy. HL is divided into four main forms: classic mixed cellularity HL (MCCHL), lymphocyte-rich Hodgkin's lymphoma (LRCHL), classic lymphocyte-depleted Hodgkin's lymphoma (LDCHL), and nodular lymphocyte-predominant HL (NLPHL). Tumor cells that predominate in this disease are called Hodgkin and Reed-Sternberg (HRS) cells. These forms of HL differ in the morphology and immunophenotype of the lymphoma cells, the composition of the lymphoma microenvironment, and their clinical behavior. While the treatment of HL is a great success story and although HL is the first lymphoid malignancy to be recognized with its first description more than 150 years ago, its biology and pathogenesis have long been enigmatic. The main reason for this is the rarity of tumor cells in the affected lymph nodes, which greatly hampered their molecular analysis. As part of this work, the health care of patients with Hodgkin's lymphoma, which represents a major challenge in nursing care, was analyzed. Less
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:122:825833
Study programmeTitle: Nursing
Study programme type: professional
Study level: undergraduate
Academic / professional title: stručni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) sestrinstva (stručni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) sestrinstva)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2023-07-19 13:42:42
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