Cranio-cerebral injuries, as one of the most challenging issues in neurotraumatology, can have far-reaching consequences for patients. These injuries often occur as a result of traffic accidents, falls, violence, or sports injuries and are a leading cause of death and disability among younger people. A crucial role in the care of these patients is played by nurses and technicians, whose interventions and care can significantly impact treatment outcomes. The skull and brain, as the most protected parts of the human body, are frequently exposed to injuries such as skull fractures, concussions, brain contusions, and various types of hematomas. Each of these injuries requires a specific diagnostic procedure, often involving imaging techniques such as computerized tomography (CT) or magnetic resonance imaging (MRI) to precisely determine the extent of damage. In addition to diagnostic methods, the use of the Glasgow Coma Scale (GCS) has become the gold standard for assessing the consciousness of patients. Accurate patient assessment using the GCS allows for a swift response and appropriate medical intervention, which is crucial in reducing the risk of permanent damage or death. Nurses and technicians, through their knowledge and experience, contribute to the diagnosis and treatment of patients with cranio-cerebral injuries throughout the entire care process—from the initial assessment and stabilization, participation in diagnostic procedures, to preoperative and postoperative care. Their role is not only technical but also emotional, as they provide psychological support to patients and their families, educating them about recovery and preventive measures. Through a multidisciplinary approach and coordinated teamwork, nurses and technicians ensure holistic care essential for patients with severe neurotraumatic injuries.