Ulcus cruris, a chronic wound on the lower leg, represents a serious health issue, particularly among the elderly and patients with chronic conditions. The most common cause is chronic venous insufficiency, which leads to blood stasis, swelling, and the development of ulcers. Timely diagnostics, such as Doppler ultrasound and the Ankle-Brachial Pressure Indeks (ABPI) test, are crucial for successful treatment. This paper analyzes the clinical characteristics, diagnostic procedures, and treatment principles of ulcus cruris, with an emphasis on an individualized approach. Systemic treatment includes improving circulation, nutrition, and managing chronic diseases, while local therapy involves wound cleaning, infection prevention, and the use of advanced dressings. Conservative methods like compression therapy and negative pressure therapy accelerate healing, while oxygen therapy and surgical interventions play a significant role in more severe cases. Treatment often requires a multidisciplinary approach due to the complexity and complications, such as infections and gangrene, which reduce patients' quality of life. The role of nurses in caring for patients with chronic wounds is crucial, as they not only provide physical care but also offer psychological support, recognize complications, and adjust interventions to improve patients' quality of life.