Palliative care is a model of care that is applied to patients who are in the terminal stage or suffer from incurable diseases whose symptoms of classical curative medicine no longer have the desired effect. The goals of care, instead of curing and prolonging life, are aimed at eliminating unpleasant and painful symptoms. It is carried out by a multidisciplinary team, and with an interdisciplinary and holistic approach, it provides support to patients and families in the form of physical, psychological, spiritual, and social care. The paper aims to show the recorded effects of physiotherapy procedures on the quality of life of palliative patients and their families by analyzing the available literature. Although palliative care is not intended only for the elderly population, demographic data indicate an increase in the old population, with a simultaneous decrease in the number of the young population. Such a trend requires the development of strategies and methods that enable people with a chronic course of the disease to have a better quality of life. The physiotherapist plays an important role in palliative care and strives to preserve the functionality and dignity of the patient with an emphasis on pain relief. The application of palliative principles in clinical practice enables an individualized approach to the patient that focuses on quality instead of quantity of life while preserving autonomy and dignity. It enables the participation of the patient in the planning of procedures, which implies good communication between all health and non-health professionals involved in care, as well as patient information. In addition to pain, which is the most common physical symptom of palliative patients, total pain is also often present, which is the product of physical, psychological, and spiritual pain that the patient feels. Considering the needs of the patient, the possibilities, and the environment in which it is carried out, palliative care can be carried out at several levels: palliative approach, general palliative care, specialist palliative care, and centers of excellence. The patient care team strives to provide care with an interdisciplinary approach that implements the various procedures and methods of the health professionals involved in the care. Each of the team members approaches the problem from a different point of view, but all interventions are aimed at the level of quality of life and its maintenance until the moment of death. Physiotherapy procedures are aimed at preserving functionality, positioning, removing pain and other unpleasant symptoms, and preventing possible complications that arise as a result of prolonged rest. The methods and interventions used include assessment, proper positioning, active, passive, and actively assisted exercises, verticalization, massage, gait training, education on the use of aids, education on energy management methods during the day, and all other procedures that positively affect the patient's state. Interventions are adapted to the patient's possibilities and wishes, and special techniques and passive methods such as electrotherapy and thermotherapy are included as a supplement to the therapy. The emphasis is on maintaining important functions for the patient, such as self-care and as much independence as possible in performing daily activities. In addition to the physical components, physiotherapy procedures have a positive effect on the psychological components of health, especially if the patient actively participates in planning the therapy and setting goals in agreement with the physiotherapist.