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undergraduate thesis
Antifungalno djelovanje novosintetiziranih kvarternih amonijevih soli
2024. urn:nbn:hr:122:639276
Ivančan, Petra
University North
University centre Koprivnica

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Ivančan, P. (2024). Antifungalno djelovanje novosintetiziranih kvarternih amonijevih soli (Undergraduate thesis). Koprivnica: University North. Retrieved from https://urn.nsk.hr/urn:nbn:hr:122:639276

Ivančan, Petra. "Antifungalno djelovanje novosintetiziranih kvarternih amonijevih soli." Undergraduate thesis, University North, 2024. https://urn.nsk.hr/urn:nbn:hr:122:639276

Ivančan, Petra. "Antifungalno djelovanje novosintetiziranih kvarternih amonijevih soli." Undergraduate thesis, University North, 2024. https://urn.nsk.hr/urn:nbn:hr:122:639276

Ivančan, P. (2024). 'Antifungalno djelovanje novosintetiziranih kvarternih amonijevih soli', Undergraduate thesis, University North, accessed 03 March 2025, https://urn.nsk.hr/urn:nbn:hr:122:639276

Ivančan P. Antifungalno djelovanje novosintetiziranih kvarternih amonijevih soli [Undergraduate thesis]. Koprivnica: University North; 2024 [cited 2025 March 03] Available at: https://urn.nsk.hr/urn:nbn:hr:122:639276

P. Ivančan, "Antifungalno djelovanje novosintetiziranih kvarternih amonijevih soli", Undergraduate thesis, University North, Koprivnica, 2024. Available at: https://urn.nsk.hr/urn:nbn:hr:122:639276

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Metadata
TitleAntifungalno djelovanje novosintetiziranih kvarternih amonijevih soli
Title (english)Antifungal activity of newly synthesized quaternary ammonium salts
AuthorPetra Ivančan
MentorBojan Šarkanj (mentor)
MentorMarija Jozanović (komentor)
Committee memberKrunoslav Hajdek (predsjednik povjerenstva)
Committee memberBožo Smoljan (član povjerenstva)
Committee memberBojan Šarkanj (član povjerenstva)
Committee memberMarija Jozanović (član povjerenstva)
Committee memberIvana Dodlek Šarkanj (član povjerenstva)
GranterUniversity North
(University centre Koprivnica)
Koprivnica
Defense date and country2024-09-18, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Zbog napretka znanosti, osim antibakterijskih testova od sve veće su važnosti antifungalni testovi. Glavni cilj ovih testova je pronaći MIC vrijednost, koja pokazuje najnižu koncentraciju antifungalnog djelotvornog sredstva (agensa), koja zaustavlja (barem polovicu ili 50% ili manje mikroorganizama, nego u kontroli rasta) vidljivi rast nakon inkubacije. U ovom radu su korišteni antifunglani mikrotestovi za ispitivanje antifungalne aktivnosti novosintetiziranih kvarternih amonijevih soli Cilj ovog rada bio je ispitati antifunglano djelovanje novosintetiziranih kvaternih amonijevih soli na pojedine vrste iz rodova plijesni Fusarium spp., Alternaria spp. Aspergillus spp. Penicillium spp. i kvasaca iz roda Candida spp. Antifungalno djelovanje ispitano je pomoću mikrotesta na mikrotitarskim pločicama. Korišteno je 16 novosintetiziranih kvarternih amonijevih soli od kojih se najučinkovitijim pokazao 3-heksadecil-1-vinil-1H-imidazol-3-ium bromid za kvasce, koji pokazuje izvrstan antifungalni učinak. Kod plijesni su najčešće izvrstan antifungalni učinak imali spojevi od 1 do 5 (3-oktadecil-1-vinil-1H-imidazol-3-ium bromid, 3-heksadecil-1-vinil-1H-imidazol-3-ium bromid, 3-ikozil-1-vinil-1H-imidazol-3-ium bromid, 3-terrtadecil-1-vinil-1H-imidazol-3-ium bromid, 1,3-didecil-2-metil-1H-imidazol-3-ium). Kod nekih plijesni i kvasaca određeni spojevi potiču njihov rast. Takvi spojevi mogu se koristiti i kao dodatak mikrobiološkim podlogama kojima će se poboljšati rast i razvoj specifičnih vrsta mikroorganizama za koje ima poboljšana svojstva rasta.
Abstract (english)
Due to the progress of science, in addition to antibacterial tests, antifungal tests are increasingly important. The main objective of these tests is to find the MIC value, which indicates the lowest concentration of the antifungal active agent (agent), which stops (at least half or 50% or less of microorganisms than in growth control) visible growth after incubation. In this work, antifungal microassays are used to test the antifungal activity of newly synthesized quaternary ammonium salts The aim of this work was to test the antifungal activity of newly synthesized quaternary ammonium salts on certain types of mold genera Fusarium spp., Alternaria spp. Aspergillus spp. Penicillium spp. and yeasts from the genus Candida spp. The antifungal activity was tested using a microtest on microtiter plates. 16 newly synthesized quaternary ammonium salts were used, the most effective of which was 3-hexadecyl-1-vinyl-1H-imidazol-3-ium bromide for yeasts, which shows an excellent antifungal effect. In the case of molds, compounds 1 to 5 (3-octadecyl-1-vinyl-1H-imidazol-3-ium bromide, 3-hexadecyl-1-vinyl-1H-imidazol-3-ium bromide, 3- icosyl-1-vinyl-1H-imidazol-3-ium bromide, 3-tertadecyl-1-vinyl-1H-imidazol-3-ium bromide, 1,3-didecyl-2-methyl-1H-imidazol-3-ium). In some molds and yeasts, certain compounds stimulate their growth. Such compounds can also be used as an addition to microbiological media, which will improve the growth and development of specific types of microorganisms for which the growth properties are improved.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:122:639276
Study programmeTitle: Food Technology
Study programme type: professional
Study level: undergraduate
Academic / professional title: prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije (prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije)
Type of resourceText
File originBorn digital
Access conditionsOpen access
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Created on2025-03-03 13:09:25