The basics of the milling process, different types of milling machines and some of the milling tools are described in the first part of the thesis. Also, it is possible to use holemaking drill bits on the milling machine, which can be used to perform operations such as drilling, expanding, countersinking, reaming and threading. Some of the holemaking tools are described in the next part of the thesis. With helicoidal milling, it is possible to drill holes using a milling cutter in such a way that the milling cutter moves in a spiral path. After that, the methods for calculating some of the drilling parameters are described. In the further part of the thesis, the practical part of the assignment, the machine on which the assingment was made, the keyboard of the control module of the machine and the VPS function of the control module of the machine are described. Using VPS, it is possible to get already complete programs by entering parameters. The process by which the zero points were obtained is described and the selected parameters for the completion of the assignment and the generation of the G-code are listed. Finally, the importance of CNC milling in today's industry is described in the conclusion of the thesis. By using CNC and VPS function, it is possible to greatly improve productivity and simplify complex machining.